Study type: Medical/biological study (experimental study)

Effects of modulated and continuous microwave irradiation on pyroantimonate precipitable calcium content in junctional complex of mouse small intestine med./bio.

Published in: Scanning Microsc 1993; 7 (4): 1255-1261
Journal partially peer-reviewed/peer-review process unclear

Aim of study (acc. to author)

To investigate the effects of amplitude modulated (AM) and continuous wave (CW) microwave exposure on the intracellular calcium distribution in mouse small intestine epithelial cells.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2.45 GHz
Modulation type: CW
Exposure duration: continuous for 3 h
  • SAR: 1.64 mW/g average over time (unspecified) (8.86 J/g at 1000 µW/cm²)
  • SAR: 330 µW/g average over time (unspecified) (1.78 J/g at 200 µW/cm².)
  • power density: 10 W/m² maximum
  • SAR: 820 µW/g average over time (unspecified) (4.43 J/g at 500 µW/cm²)
Exposure 2: 2.45 GHz
Modulation type: AM
Exposure duration: continuous for 3 h
  • power density: 1 W/m² minimum (500 µW/cm²)
  • SAR: 820 µW/g average over time (unspecified) (4.43 J/g at 500 µW/cm²)
  • power density: 10 W/m² maximum
  • SAR: 1.64 mW/g average over time (unspecified) (8.86 J/g at 1000 µW/cm²)
  • SAR: 330 µW/g average over time (unspecified) (1.78 J/g at 200 µW/cm²)

Exposure 1

Main characteristics
Frequency 2.45 GHz
Type
Waveform
Exposure duration continuous for 3 h
Modulation
Modulation type CW
Exposure setup
Exposure source
Chamber anechoic room/2.55 x 1.8 m x 2.9 m
Setup circular plastic container (diameter 23cm, 5cm high) divided into 10 cages. The animals were placed head to head in the opposite cages of the container such that the long axis of their body was parallelt o electric field.
Additional info Control animals were kept for 3 hours in similar boxes without irradiation.
Parameters
Measurand Value Type Method Mass Remarks
SAR 1.64 mW/g average over time calculated unspecified 8.86 J/g at 1000 µW/cm²
SAR 330 µW/g average over time calculated unspecified 1.78 J/g at 200 µW/cm².
power density 10 W/m² maximum measured - -
SAR 820 µW/g average over time calculated unspecified 4.43 J/g at 500 µW/cm²

Exposure 2

Main characteristics
Frequency 2.45 GHz
Type
Waveform
Exposure duration continuous for 3 h
Modulation
Modulation type AM
Modulation frequency 16 Hz
Additional info

on/off ratio: 50-50%

Exposure setup
Exposure source
Parameters
Measurand Value Type Method Mass Remarks
power density 1 W/m² minimum measured - 500 µW/cm²
SAR 820 µW/g average over time calculated unspecified 4.43 J/g at 500 µW/cm²
power density 10 W/m² maximum measured - -
SAR 1.64 mW/g average over time calculated unspecified 8.86 J/g at 1000 µW/cm²
SAR 330 µW/g average over time calculated unspecified 1.78 J/g at 200 µW/cm²

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

AM microwave exposure at higher energies (0.5 and 1,0 mW/cm2) leads to noticeable alterations in calcium distribution. These changes occured reversible 24 h after exposure.
CW microwave exposure and AM microwave exposure with 0.1 mW/cm2 did not alter the distribution of calcium.

Study character:

Study funded by