Study type: Medical/biological study (experimental study)

Ethanol-induced hypothermia and ethanol consumption in the rat are affected by low-level microwave irradiation med./bio.

By: Lai H, Horita A, Chou CK, Guy AW
Published in: Bioelectromagnetics 1984; 5 (2): 213-220
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Aim of study (acc. to editor)

To study the effects of microwave irradiation on ethanol-induced hypothermia and on ethanol consumption in rats.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2.45 GHz
Modulation type: pulsed
Exposure duration: 45 min
Exposure 2: 2.45 GHz
Modulation type: pulsed
Exposure duration: 90 min on day 4 , day 8 and day 9

Exposure 1

Main characteristics
Frequency 2.45 GHz
Type
Charakteristic
  • guided field
Exposure duration 45 min
Modulation
Modulation type pulsed
Pulse width 2 µs
Packets per second 500
Exposure setup
Exposure source
Additional info Control animals (n= 14)were sham irradiated simultaneously in similar waveguides
Parameters
Measurand Value Type Method Mass Remarks
power density 10 W/m² mean unspecified - -
SAR 600 µW/g unspecified calculated - determined calorimetrically

Exposure 2

Main characteristics
Frequency 2.45 GHz
Type
Charakteristic
  • guided field
Exposure duration 90 min on day 4 , day 8 and day 9
Additional info 48 rats were used in this experiment
Modulation
Modulation type pulsed
Pulse width 2 µs
Repetition frequency 500 Hz
Exposure setup
Exposure source
Additional info Animals were kept in the waveguide for 9 days but only exposed on day 4 , day 8 and day 9. Half of the aminals were exposed on a specific exposure day while the other half were sham irradiated.
Parameters
Measurand Value Type Method Mass Remarks
power density 10 W/m² mean - - -
SAR 600 µW/g unspecified calculated - determined calorimetrically

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Animals injected with ethanol immediately after microwave exposure exhibited attenuation of the initial rate of fall in body temperature, which was elicited by the ethanol, but exhibited no significant difference in maximal hypothermia as compared with that of sham-exposed animals. Microwave exposure did not affect the consumption of a sucrose solution by water-deprived rats. However, it enhanced the consumption of a solution of sucrose + ethanol by water-deprived rats.

Study character:

Study funded by

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