Study type: Medical/biological study (experimental study)

In vitro microwave effects on human neutrophil precursor cells (CFU-C) med./bio.

By: Ottenbreit MJ, Lin JC, Inoue S, Peterson Jr WD
Published in: Bioelectromagnetics 1981; 2 (3): 203-215
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Aim of study (acc. to author)

To investigate the effects of 2450 MHz CW microwave exposure on the colony forming ability of human bone marrow cells in vitro.

Background/further details

Prior examination exposed cells were cultured for a period of 6-7 and 12-14 days respectively.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2.45 GHz
Modulation type: CW
Exposure duration: continuous for 15 min
  • SAR: 2,000 mW/g maximum (62 - 2000 mW/g)
  • power density: 1,000 mW/cm² maximum (31, 62, 125, 250, 500, 1000 mW/cm²)

General information

the experiments were performed at different constant temperatures

Exposure 1

Main characteristics
Frequency 2.45 GHz
Type
Exposure duration continuous for 15 min
Modulation
Modulation type CW
Exposure setup
Exposure source
Chamber cells in glass microcapillary tubes inside an exposure chamber containing 0.9% saline solution continuously circulated by a constant temperature circulator
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
SAR 2,000 mW/g maximum calculated - 62 - 2000 mW/g
power density 1,000 mW/cm² maximum measured - 31, 62, 125, 250, 500, 1000 mW/cm²

Reference articles

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

At low power desities (up to 62 mW/cm2) no reduction in neutrophil colony number was observed. However, at higher power densities a reduction was observed. This reduction did not depend on temperature rise or cell cycle state.

Study character:

Study funded by

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