Study type: Medical/biological study (experimental study)

The effect of exposure of acetylcholinesterase to 2,450-MHz microwave radiation med./bio.

By: Millar DB, Christopher JP, Hunter J, Yeandle SS
Published in: Bioelectromagnetics 1984; 5 (2): 165-172
Download citation in RIS format

Aim of study (acc. to author)

To investigate the effect of microwave radiation on the enzyme acetylcholinesterase in vitro during exposure. The enzyme was isolated from the electroplax tissue of the ray Narcine brasiliensis. Electroplax tissue as found in electric fishes are a good source for acetylcholinesterase due to the fact that these specialised muscle fibres generate extremely high voltages in response to nervous stimulation.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2.45 GHz
Modulation type: pulsed
Exposure 2: 2.45 GHz
Modulation type: pulsed
Exposure 3: 2.375–2.7 GHz
Modulation type: pulsed
Exposure 4: 2.45 GHz
Modulation type: pulsed
Exposure 5: 2.45 GHz
Modulation type: pulsed
Exposure 6: 2.5 kHz
Modulation type: pulsed

General information

Effects of 2.45 GHz radiation.

Exposure 1

Main characteristics
Frequency 2.45 GHz
Modulation
Modulation type pulsed
Additional info

Duty cycle: 0.003. Various signals were applied with 4.8 µs pulse width and 625 repetition rate, 2.4 µs and 1250 repetition rate and 1.2 µs and 2500 repetition rate.
Exposure setup
Parameters
Measurand Value Type Method Mass Remarks
SAR 2.46 W/g mean calculated - -
SAR 4 mW/g mean calculated - -

Exposure 2

Main characteristics
Frequency 2.45 GHz
Modulation
Modulation type pulsed
Pulse width 8 µs
Duty cycle 0.0004 %
Repetition frequency 50 Hz
Exposure setup
Parameters
Measurand Value Type Method Mass Remarks
SAR 34 mW/g mean calculated cf. remarks averaged absorbed power: 6.9 mW
SAR 13 mW/g mean calculated cf. remarks averaged absorbed power: 2.6 mW
SAR 330 mW/g mean calculated cf. remarks averaged absorbed power: 68 mW
SAR 180 mW/g mean calculated cf. remarks averaged absorbed power: 36 mW

Exposure 3

Main characteristics
Frequency 2.375–2.7 GHz
Additional info Frequencies: 2.375 GHz, 2.425 GHz, 2.5 GHz, 2.55 GHz, 2.625 GHz and 2.7 GHz.
Modulation
Modulation type pulsed
Pulse width 16.7 µs
Duty cycle 0.0005 %
Repetition frequency 30 Hz
Exposure setup
Parameters
Measurand Value Type Method Mass Remarks
SAR 40 mW/g mean calculated cf. remarks at 2.425 GHz
SAR 32 mW/g mean calculated cf. remarks at 2.7 GHz
SAR 44 mW/g mean calculated cf. remarks at 2.55 GHz
SAR 42 mW/g mean calculated cf. remarks at 2.372 GHz
SAR 42 mW/g mean calculated cf. remarks at 2.5 GHz
SAR 35 mW/g mean calculated cf. remarks at 2.625 GHz

Exposure 4

Main characteristics
Frequency 2.45 GHz
Modulation
Modulation type pulsed
Duty cycle 0.0004 %
Additional info

Repitition rate: 10 pulses/sec to 90 pulses/sec.
Exposure setup
Parameters
Measurand Value Type Method Mass Remarks
SAR 1.9 W/g mean calculated - -

Exposure 5

Main characteristics
Frequency 2.45 GHz
Modulation
Modulation type pulsed
Repetition frequency 50 Hz
Additional info

Various duty cycles were applied: 0.0008, 0.0016 and 0.0032
Exposure setup
Parameters
Measurand Value Type Method Mass Remarks
SAR 1.75 W/g mean calculated - -

Exposure 6

Main characteristics
Frequency 2.5 kHz
Modulation
Modulation type pulsed
Pulse width 1.2 µs
Repetition frequency 2,500 Hz
Exposure setup
Parameters
Measurand Value Type Method Mass Remarks
SAR 483 mW/g mean calculated - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • during exposure

Main outcome of study (acc. to author)

No significant effect of microwave exposure on enzyme activity was found.

Study character:

Study funded by

Related articles