Study type: Medical/biological study (experimental study)

Low-frequency electromagnetic field effects on functional groups in human skin keratinocytes cells revealed by IR-SNOM med./bio.

By: Cricenti A, Generosi R, Luce M, Perfetti P, Sanghera JS, Aggarwal ID, Tolk NH, Vobornik D, Margaritondo G, Piston DW, Manni V, Grimaldi S, Lisi A, Rieti S
Published in: J Microsc 2008; 229 Pt 3: 551-554
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Aim of study (acc. to editor)

This study was conducted to examine effects of extremely low frequency electromagnetic fields exposure on functional groups in human keratinocytes.

Background/further details

The temperature was maintained at 37 +/- 0.3 °C.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 50 Hz
Exposure duration: continuous for 24 h

Exposure 1

Main characteristics
Frequency 50 Hz
Type
Waveform
Exposure duration continuous for 24 h
Exposure setup
Exposure source
Setup cells placed inside the temperature-regulated solenoid
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 1 mT effective value - - -
electric field strength 0.001 µV/cm - estimated - -

Reference articles

  • Rieti S et al. (2004): SNOM and AFM microscopy techniques to study the effect of non-ionizing radiation on the morphological and biochemical properties of human keratinocytes cell line (HaCaT)

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Human keratinocytes, exposed for 24 hours to a 1 mT 50 Hz sinusoidal magnetic field showed detectable changes in distribution of chemical functional groups and cellular shape.

Study character:

Study funded by

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