Study type:
Epidemiological study
(observational study)
Residential magnetic fields, medication use, and the risk of breast cancer
epidem.
By:
Davis S, Mirick DK
Published in: Epidemiology 2007; 18 (2): 266-269
Aim of study (acc. to author)
Further details
Participants of the study (publication 8545) were recontacted and interviewed regarding medication use during the 10 years before diagnosis. Regular use of medication was defined as use at least 4 days a week for 6 months or longer. The interview included following medication classes previously shown to be associated with reduced melatonin levels (publication 7471): calcium channel or beta blocker, psychotherapeutics, corticosteroids, and nonsteroidal anti-inflammatory drugs.
Endpoint/type of risk estimation
Type of risk estimation:
(odds ratio (OR))
Exposure
Assessment
Exposure groups
Group
|
Description
|
Group 1
|
mean nighttime bedroom magnetic field level (constructed variable)
|
Population
-
Group:
-
Age:
20–74 years
-
Observation period:
November 1992 - March 1995, March 2000 - December 2001
-
Study location:
USA (Seattle area, Washington)
Case group
-
Characteristics:
breast cancer
-
Data source:
Fred Hutchinson Cancer Research Centre, Seattle
-
Exclusion criteria:
not English-speaking, non-Caucasian
Control group
-
Selection:
-
Matching:
- sex
- area
- ethnicity
- 5-year age group
- case:control = 1:1
Study size
|
Cases |
Controls |
Eligible |
813 |
793 |
Participants |
558 |
588 |
Statistical analysis method:
- conditional logistic regression
(
adjustment:
)
Results (acc. to author)
Study funded by
-
National Cancer Institute (NCI; U.S. National Institutes of Health), Maryland, USA
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Davis S et al.
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-
Schoenfeld ER et al.
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-
London SJ et al.
(2003):
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