Study type: Medical/biological study (experimental study)

Decrease of luminol chemiluminescence upon exposure of human blood serum to 50 Hz electric fields med./bio.

By: Calota V, Dragoiu S, Meghea A, Giurginca M
Published in: Bioelectrochemistry 2006; 69 (1): 126-127
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Aim of study (acc. to editor)

To study the effect of an electric field (AC) on luminol chemiluminescence of human serum.

Background/further details

Measurement of luminol chemiluminescence seems to be a marker for free radicals in this assay used (methodological background not explained in the paper).

Endpoint

Exposure

Exposure Parameters
Exposure 1: 50 Hz
Exposure duration: continuous for 1 h and 2 h

Exposure 1

Main characteristics
Frequency 50 Hz
Type
Waveform
Exposure duration continuous for 1 h and 2 h
Exposure setup
Exposure source
Setup The serum samples were positioned between the plates. The electric field in this region was uniform and homogeneous.
Parameters
Measurand Value Type Method Mass Remarks
electric field strength 5 kV/cm unspecified unspecified - -
electric field strength 7.5 kV/cm unspecified unspecified - -
electric field strength 10 kV/cm unspecified unspecified - -
electric field strength 15 kV/cm unspecified unspecified - -
electric field strength 20 kV/cm unspecified unspecified - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • during exposure

Main outcome of study (acc. to author)

The luminol chemiluminescence decreased during 1 and 2 h exposure of human serum to 50 Hz electric fields of different intensities as compared to the controls. This indicates an electric field-induced decrease in the concentration of the free radicals.

Study character:

Study funded by